Pain coping skills training (PSCT) is beneficial for patients on maintenance hemodialysis who experience chronic pain, according to a study published online on December 30 in JAMA Internal Medicine.
Laura M. Dember, MD, of the Perelman School of Medicine of the University of Pennsylvania in Philadelphia, and colleagues examined the effectiveness of a cognitive behavioral intervention, PSCT, on pain interference in a multicenter, randomized clinical trial. Adults receiving and experiencing maintenance hemodialysis chronic pain were randomly assigned to PSCT or usual care (319 and 324 participants, respectively).
The researchers found that the PSCT group had a greater reduction in the Brief Pain Inventory (BPI) Interference score than the usual care group at week 12 (between-group difference, −0.49). At 24 weeks, the effect persisted (between-group difference in BPI interference score, −0.48), but the effect was attenuated at week 36 (between-group difference, −0.34). A decrease in BPI interference score of more than 1 point (minimal clinically important difference) occurred in 50.9 and 36.6 percent of patients in the PSCT and usual care groups, respectively, at 12 weeks and in 55.0 versus 42 .8 percent after 24 weeks. (odds ratios 1.79 and 1.59 respectively). For secondary outcomes, favorable changes were also observed for PSCT.
“While the effect on the overall cohort was modest in magnitude, the intervention resulted in clinically meaningful improvement in pain interference for a substantial proportion of participants,” the authors write.
Several authors revealed ties to the pharmaceutical industry.
More information:
Laura M. Dember et al, Pain Management Skills Training for Patients Undergoing Hemodialysis, JAMA Internal Medicine (2024). DOI: 10.1001/jamainintermed.2024.7140
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